A team of 12 undergraduate students at UT Austin received top awards at the International Genetically Engineered Machine (iGEM) Competition, including placing in the top 10 overall in the undergraduate category—the only team from the U.S. to do so.
Scientists from The University of Texas at Austin report in the journal Science that they have developed a new strategy to protect honey bees from a deadly trend known as colony collapse: genetically engineered strains of bacteria.
A team of undergraduate researchers involved with the Department of Molecular Biosciences received awards in two categories at the 2019 International Genetically Engineered Machine (iGEM) Jamboree, the largest showcase of synthetic biology innovations in the world.
As any farmer or summer gardener knows, tiny aphids represent an enemy for most crops. The insects like many of the same plants that we rely on for food, and aphids can sometimes spread plant diseases, similar to the way mosquitos spread human diseases.
A team of synthetic biologists led by Steven Benner at the Foundation for Applied Molecular Evolution—and including Andy Ellington at The University of Texas at Austin—have synthesized a new kind of DNA that uses eight building blocks instead of the four found in all earthly life. Reporting today in the journal Science, the researchers suggest the new eight-letter DNA could find applications in medicine and biological computing. The finding also has implications for how scientists think about life elsewhere in the universe.
Scientists have long dreamed of creating synthetic structures out of the same raw material that nature uses in living systems — proteins — believing such an advance would allow for the development of transformative nanomachines, for example, molecular cages that precisely deliver chemotherapy drugs to tumors or photosynthetic systems for harvesting energy from light. Now a team of biologists from The University of Texas at Austin and the University of Michigan have invented a way to build synthetic structures from proteins, and just as in nature, the method is simple and could be used for a variety of purposes.
A new diagnostic tool has been developed by researchers at The University of Texas at Austin that can easily, quickly and cheaply identify whether a mosquito belongs to the species that carries dangerous diseases such as Zika virus, dengue, chikungunya or yellow fever. It can also determine whether the bug has come into contact with a mosquito-control strategy known as Wolbachia.
In the same way that barcodes on your groceries help stores know what's in your cart, DNA barcodes help biologists attach genetic labels to biological molecules to do their own tracking during research, including of how a cancerous tumor evolves, how organs develop or which drug candidates actually work. Unfortunately with current methods, many DNA barcodes have a reliability problem much worse than your corner grocer's. They contain errors about 10 percent of the time, making interpreting data tricky and limiting the kinds of experiments that can be reliably done.
By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.
Despite a billion years of evolution separating humans from the baker’s yeast in their refrigerators, hundreds of genes from an ancestor that the two species have in common live on nearly unchanged in them both, say biologists at The University of Texas at Austin. The team created thriving strains of genetically engineered yeast using human genes and found that certain groups of genes are surprisingly stable over evolutionary time.
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