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Scientists from The University of Texas at Austin took an important step toward safer gene-editing cures for life-threatening disorders, from cancer to HIV to Huntington's disease, by developing a technique that can spot editing mistakes a popular tool known as CRISPR makes to an individual's genome. The research appears today in the journal Cell.

With prices down and weather patterns unpredictable, these are tough times for America's cotton farmers, but new research led by Z. Jeffrey Chen at The University of Texas at Austin might offer a break for the industry. He and a team have taken the first step toward a new way of breeding heartier, more productive cotton through a process called epigenetic modification.

Students have selected Jessie Zhang, an associate professor of molecular biosciences, as The University of Texas at Austin's Professor of the Year. 

With funding from the highly competitive Human Frontier Science Program, an international team including The University of Texas at Austin's Andrew Ellington plans to unravel billions of years of evolution to create an ancient version of a cell. 

Robed in tie-dye lab coat, graduate student Norah Ashoura meticulously guides her pipette while explaining what Star Wars has to do with the innovative research into cancer treatments coming from the George Georgiou lab group.

Just as the fossil record reveals clues about the conditions in which prehistoric animals and plants once lived, newly discovered genetic signatures in bacterial evolution may one day allow hospitals, doctors and scientists to know more about the environment where a bacterial infection originated.

A research team led by scientists at The University of Texas Austin has engineered an enzyme that safely treats prostate and breast cancer in animals and also lengthens the lifespan of models that develop chronic lymphocytic leukemia. The new treatment and results from preclinical trials are described in a paper published in the Nov. 21 issue of Nature Medicine.

For healthy cells to become cancerous cells, they have to lose several systems that regulate healthy function such as cell growth and division and DNA repair. New findings from University of Texas at Austin researchers about how one such regulatory system works could aid in efforts to develop personalized treatments for cancer.

A team of engineers and scientists at The University of Texas at Austin is reporting new findings on how the influenza vaccine produces antibodies that protect against disease, research that suggests that the conventional flu vaccine can be improved. The findings were reported in the journal Nature Medicine on Nov. 7.

As we head into flu season, researchers at The University of Texas at Austin are announcing the results of three flu studies: One suggests a possible new target for drugs to combat the flu; another study forecasts how effective this year's flu vaccine might be; and a third looks at ways to improve the process of identifying flu strains in the wild and thus improve how strains are selected for inclusion in each year's vaccine.

Update, October 2020: The 2020 Nobel Prize for Chemistry was awarded to two researchers, Emmanuelle Charpentier and Jennifer A. Doudna, "for the development of a method for genome editing." The two scientists discovered CRISPR-Cas9, genetic scissors which are based on a natural defense mechanism bacteria use against viruses, and showed that the tool can be used to precisely edit any DNA. Doudna was an advisor to David Taylor, featured in the piece below, while he was a postdoctoral researcher at the University of California, Berkeley.​

Update, October 2017: ​The 2017 Nobel Prize for Chemistry was awarded to three researchers who developed cryo-electron microscopy, a method that allows biochemists to "freeze biomolecules mid-movement and visualize processes they have never previously seen." This fall, UT Austin has opened its own cryo-EM facility, where researchers are beginning to explore new insights into the chemistry of life. Read on to learn about one of the faculty members involved with the new Sauer Laboratory for Structural Biology, and work planned within the College of Natural Sciences. 

Scientists studying how microbes evolve have long assumed that nearly all new genetic mutations get passed down at a predictable pace and usually without either helping or hurting the microbe in adapting to its environment. In a new study published in the journal Nature, an international team of researchers studying tens of thousands of generations of E. coli bacteria report that most new genetic mutations that were passed down were actually beneficial and occurred at much more variable rates than previously thought.

Researchers from The University of Texas at Austin and elsewhere have determined that two bacterial species commonly found in the human mouth and in abscesses, cooperate to make the pathogenic bacterium, Aggregatibacter actinomycetemcomitans, more infectious. Key to the cooperation is that the harmless partner provides the pathogen with an oxygen-rich environment that helps it flourish.

For 3 billion years, one of the major carriers of information needed for life, RNA, has had a glitch that creates errors when making copies of genetic information. Researchers at The University of Texas at Austin have developed a fix that allows RNA to accurately proofread for the first time.

Scientists at The University of Texas at Austin have developed a new method to rapidly detect a single virus in urine, as reported this week in the journal Proceedings of the National Academy of Sciences.